Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.30 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25602026 | 0.94 | MDM2 (0.32) | ALKSLC6A4 | |
| SCHEMBL3147104 | 0.94 | ALK (0.33) | ALK | |
| SCHEMBL25714230 | 0.92 | ALK (0.35) | ALKPDK2DYRK3CLK1CLK2 | |
| SCHEMBL25602145 | 0.91 | ALK (0.40) | ALK | |
| SCHEMBL25602579 | 0.91 | PGR (0.34) | ALKDYRK3CLK1CLK2SRPK2 | |
| SCHEMBL25714814 | 0.91 | PGR (0.34) | ALKDYRK3CLK1CLK2SRPK2 | |
| SCHEMBL25602258 | 0.91 | ALK (0.43) | ALK | |
| SCHEMBL3146162 | 0.90 | TDP1 (0.30) | — | |
| SCHEMBL25603870 | 0.89 | — | — | |
| SCHEMBL25714240 | 0.89 | ALK (0.33) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1872173-B9 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL INC (US) | 2011-01-05 | — | — | EP | claimed |
| EP-1872173-B1 | PHOTOCHROMIC MATERIALS HAVING EXTENDED PI-CONJUGATED SYSTEMS AND COMPOSITIONS AND ARTICLES INCLUDING THE SAME | TRANSITIONS OPTICAL INC (US) | 2010-04-14 | — | — | EP | claimed |
| EP-4270067-A1 | PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND GLASSES | Hoya Lens Thailand Ltd. (TH) | 2023-11-01 | — | — | EP | disclosed |
| US-20230340318-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | HOYA LENS THAILAND LTD. (TH) | 2023-10-26 | — | — | US | disclosed |
| US-20230227717-A1 | PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-07-20 | — | — | US | disclosed |
| EP-4198102-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | Hoya Lens Thailand Ltd. (TH) | 2023-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340318-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | NR2E3, CRY1, RPS10 | ALK 2627/4885NPY5R 2347/4885PDK2 2722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.