Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267932 | 0.89 | BRD4 (0.56) | BRD4TDP2PDE4ACYP1A2TSHR | |
| SCHEMBL27492257 | 0.89 | BRD4 (0.58) | BRD4TDP2PDE4ACYP1A2TSHR | |
| SCHEMBL1514835 | 0.88 | BRD4 (0.55) | BRD4TDP2MEN1KMT2AKDM4E | |
| SCHEMBL29604747 | 0.88 | BRD4 (0.55) | BRD4TDP2MEN1KMT2AKDM4E | |
| SCHEMBL3602782 | 0.87 | L3MBTL1 (0.55) | BRD4GRM5HTTL3MBTL1GLA | |
| SCHEMBL13313473 | 0.86 | BRD4 (0.56) | BRD4TDP2PDE4ACYP1A2TSHR | |
| SCHEMBL25370578 | 0.85 | PPIA (0.60) | BRD4TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL6042670 | 0.85 | BRD4 (0.52) | BRD4TDP2PDE4AHTTL3MBTL1 | |
| SCHEMBL30852245 | 0.83 | BRD4 (0.53) | BRD4TDP2PDE4ACYP1A2HTT | |
| SCHEMBL13348591 | 0.83 | BRD4 (0.53) | BRD4TDP2PDE4ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490668-B | Compounds and compositions for the treatment of diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2025-02-25 | — | — | CN | disclosed |