Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CBLB | Q13191 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21827569 | 1.00 | APLNR (0.42) | APLNRGRM5MAPK8CBLBMEN1 | |
| SCHEMBL29596279 | 0.96 | APLNR (0.42) | APLNRGRM5MAPK8CBLBMEN1 | |
| SCHEMBL21826883 | 0.96 | APLNR (0.42) | APLNRGRM5MAPK8CBLBMEN1 | |
| SCHEMBL25537829 | 0.91 | APLNR (0.39) | APLNRGRM5MAPK8CBLBMEN1 | |
| SCHEMBL21826857 | 0.87 | CCR4 (0.39) | APLNRGRM5MAPK8MEN1KMT2A | |
| SCHEMBL21826864 | 0.86 | APLNR (0.42) | APLNRGRM5MAPK8CBLBMEN1 | |
| SCHEMBL31471102 | 0.86 | APLNR (0.42) | APLNRGRM5MAPK8CBLBMEN1 | |
| SCHEMBL31471101 | 0.85 | APLNR (0.43) | APLNRGRM5MAPK8CBLBMEN1 | |
| SCHEMBL21827065 | 0.85 | APLNR (0.43) | APLNRGRM5MAPK8CBLBMEN1 | |
| SCHEMBL31471096 | 0.84 | APLNR (0.43) | APLNRGRM5MAPK8CBLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490668-B | Compounds and compositions for the treatment of diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2025-02-25 | — | — | CN | disclosed |