Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 2/20 | 0.53 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.53 |
| ▸ | ULK1 | O75385 | 3/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 5/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471718 | 0.79 | ULK1 (0.68) | PAK4PAK1ULK1NTRK1NTRK3 | |
| SCHEMBL31471734 | 0.78 | PAK4 (0.62) | PAK4PAK1ULK1SRCGSK3B | |
| SCHEMBL31471912 | 0.78 | CDK7 (0.57) | PAK4PAK1ULK1NTRK1IGF1R | |
| SCHEMBL13054490 | 0.77 | ULK1 (0.56) | PAK4PAK1ULK1NTRK1NTRK3 | |
| SCHEMBL31471834 | 0.77 | PAK4 (0.56) | PAK4PAK1ULK1NTRK1NTRK3 | |
| SCHEMBL31471871 | 0.77 | ULK1 (0.64) | PAK4PAK1ULK1NTRK1NTRK3 | |
| SCHEMBL31471722 | 0.75 | ULK1 (0.72) | PAK4PAK1ULK1NTRK1NTRK3 | |
| SCHEMBL12430707 | 0.75 | ULK1 (0.66) | PAK4PAK1ULK1NTRK1NTRK3 | |
| SCHEMBL31471716 | 0.74 | ULK1 (0.61) | PAK4PAK1ULK1NTRK1NTRK3 | |
| SCHEMBL22054065 | 0.74 | AURKA (0.53) | NTRK1SRCGSK3BAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |