SCHEMBL31471908

SCHEMBL31471908

CC(C)(C)OC(=O)N1CC2CC1CN2S(=O)(=O)c1cccc(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.67
F13A1 P00488 1/20 0.58
TGM2 P21980 1/20 0.58
TGM1 P22735 1/20 0.58
STS P08842 1/20 0.49
HTR1A P08908 2/20 0.48
HTR7 P34969 2/20 0.48
NR1H2 P55055 7/20 0.44
RORC P51449 4/20 0.43
GPR119 Q8TDV5 1/20 0.42
NR1H3 Q13133 5/20 0.41
MMP2 P08253 1/20 0.41
PARP1 P09874 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31471830 0.88 HSD11B1 (0.68) HSD11B1F13A1TGM2TGM1NR1H2
SCHEMBL31472006 0.87 HSD11B1 (0.79) HSD11B1F13A1TGM2TGM1NR1H2
SCHEMBL31471835 0.86 HSD11B1 (0.66) HSD11B1F13A1TGM2TGM1NR1H2
SCHEMBL13950412 0.85 HSD11B1 (0.67) HSD11B1F13A1TGM2TGM1RORC
SCHEMBL31471900 0.85 HSD11B1 (0.67) HSD11B1F13A1TGM2TGM1RORC
SCHEMBL1618371 0.83 HSD11B1 (0.70) HSD11B1F13A1TGM2TGM1NR1H2
SCHEMBL31471951 0.83 HSD11B1 (0.70) HSD11B1F13A1TGM2TGM1NR1H2
SCHEMBL30121356 0.81 HSD11B1 (0.81) HSD11B1F13A1TGM2TGM1NR1H2
SCHEMBL31471842 0.81 HSD11B1 (0.76) HSD11B1F13A1TGM2TGM1HTR1A
SCHEMBL21426008 0.80 HSD11B1 (0.79) HSD11B1F13A1TGM2TGM1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025100889-A1 QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 한국화학연구원 2025-05-15 WO disclosed