Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | FADS1 | O60427 | 2/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 7/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786130 | 1.00 | APP (0.56) | APPPDE5ATRPA1FADS1AURKA | |
| SCHEMBL801931 | 0.87 | GRM4 (0.53) | APPPDE5ATRPA1FADS1AURKA | |
| SCHEMBL801842 | 0.82 | PIK3CD (0.52) | TRPA1FADS1AURKAADRA2APAK4 | |
| SCHEMBL786005 | 0.81 | CYP1A2 (0.60) | PDE5ATRPA1FADS1MAPTMEN1 | |
| SCHEMBL785429 | 0.81 | PDE5A (0.49) | PDE5ATRPA1FADS1AURKAMAPT | |
| SCHEMBL786325 | 0.81 | ABCG2 (0.61) | PDE5AAURKAMAPTKDM4EMEN1 | |
| SCHEMBL801546 | 0.80 | TRPA1 (0.48) | PDE5ATRPA1FADS1AURKAMAPT | |
| SCHEMBL2203548 | 0.80 | RAD52 (0.60) | PDE5ATRPA1FADS1AURKAMAPT | |
| SCHEMBL802318 | 0.80 | TRPA1 (0.54) | TRPA1FADS1AURKAADRA2APAK4 | |
| SCHEMBL2206804 | 0.80 | NPY5R (0.68) | TRPA1FADS1AURKAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |