Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 3/20 | 0.59 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.54 |
| ▸ | ULK1 | O75385 | 1/20 | 0.52 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471754 | 0.88 | AURKA (0.55) | NTRK1NTRK3NTRK2SRCGSK3B | |
| SCHEMBL31471945 | 0.84 | PAK4 (0.55) | PAK4PAK1IGF1RNTRK1ULK1 | |
| SCHEMBL31471946 | 0.82 | PAK4 (0.65) | PAK4PAK1IGF1RNTRK1ULK1 | |
| SCHEMBL31471922 | 0.81 | PAK4 (0.57) | PAK4PAK1NTRK1ULK1NTRK3 | |
| SCHEMBL31471803 | 0.81 | PAK4 (0.57) | PAK4PAK1IGF1RNTRK1ULK1 | |
| SCHEMBL31472008 | 0.80 | PAK4 (0.65) | PAK4PAK1IGF1RNTRK1ULK1 | |
| SCHEMBL31471894 | 0.80 | PAK4 (0.58) | PAK4PAK1NTRK1ULK1NTRK3 | |
| SCHEMBL31471916 | 0.80 | PAK4 (0.56) | PAK4PAK1IGF1RNTRK1ULK1 | |
| SCHEMBL31471895 | 0.80 | PAK4 (0.56) | PAK4PAK1IGF1RNTRK1ULK1 | |
| SCHEMBL31471725 | 0.78 | ROCK2 (0.39) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |