Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29456319 | 1.00 | CRHBP (0.37) | CRHBPCRHR2F10MTORGLA | |
| SCHEMBL21491203 | 1.00 | CRHBP (0.37) | CRHBPCRHR2F10MTORGLA | |
| SCHEMBL31472363 | 1.00 | CRHBP (0.37) | CRHBPCRHR2F10MTORGLA | |
| SCHEMBL21516870 | 0.93 | CRHBP (0.37) | CRHBPCRHR2F10MTORGLA | |
| SCHEMBL21491419 | 0.92 | CRHBP (0.38) | CRHBPCRHR2F10MTORKMT2A | |
| SCHEMBL21491307 | 0.91 | F10 (0.39) | CRHBPCRHR2F10MTORKMT2A | |
| SCHEMBL21491309 | 0.91 | F10 (0.39) | CRHBPCRHR2F10MTORKMT2A | |
| SCHEMBL30952543 | 0.91 | F10 (0.39) | CRHBPCRHR2F10MTORKMT2A | |
| SCHEMBL31472407 | 0.91 | F10 (0.39) | CRHBPCRHR2F10MTORKMT2A | |
| SCHEMBL21491448 | 0.91 | F10 (0.39) | CRHBPCRHR2F10MTORKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236428-B | Antiproliferative compounds and uses thereof | 默克专利股份有限公司 | 2025-04-01 | — | — | CN | disclosed |