⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19127826 | 0.77 | — | — | |
| SCHEMBL17239401 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL17239398 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL17239400 | 0.75 | ALDH1A1 (0.36) | — | |
| SCHEMBL17239399 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL16288842 | 0.73 | — | — | |
| SCHEMBL1081400 | 0.71 | — | — | |
| SCHEMBL2162558 | 0.71 | — | — | |
| SCHEMBL2160980 | 0.69 | — | — | |
| SCHEMBL9444567 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6475473-B1 | Perfume compositions | QUEST INTERNATIONAL B.V. (NL) | 2002-11-05 | — | — | US | claimed |
| CN-116813596-A | Macrocyclic HCV NS3 inhibits tripeptide synthesis | 吉利德科学公司 | 2023-09-29 | — | — | CN | disclosed |
| US-11718619-B2 | Isoxazolyl-carbonyloxy azabicyclo[3.2.1]octanyl compounds as FXR activators | ARDELYX, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| CN-111320610-B | Macrocyclic HCV NS3 inhibits tripeptide synthesis | 吉利德科学公司 | 2023-06-06 | — | — | CN | disclosed |
| US-20230139597-A1 | HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS | ARDELYX, INC. (US) | 2023-05-04 | — | — | US | disclosed |
| CN-115974883-A | Method for synthesizing chiral seven-membered ring bridged 3, 4-fused tricyclic indole | 河南师范大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-109970629-B | Process for preparing antifungal compounds | 迈科维亚医药公司 | 2023-04-11 | — | — | CN | disclosed |
| EP-3954684-A1 | PROCESS FOR THE PREPARATION OF HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS | Ardelyx, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| US-20210300927-A1 | ISOXAZOLYL-CARBONYLOXY AZABICYCLO[3.2.1]OCTANYL COMPOUNDS AS FXR ACTIVATORS | ARDELYX, INC. (US) | 2021-09-30 | — | — | US | disclosed |
| US-11091482-B2 | Isoxazolyl-carbonyloxy azabicyclo[3.2.1]octanyl compounds as FXR activators | ARDELYX, INC. (US) | 2021-08-17 | — | — | US | disclosed |
| WO-2005094514-A2 | HETEROARYL PIPERIDINE GLYCINE TRANSPORTER INHIBITORS | MERCK & CO., INC. (US) | 2005-10-13 | — | — | WO | disclosed |
| US-6846802-B2 | Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising N-cyclic P2 moieties | SCHERING CORPORATION (US) | 2005-01-25 | — | — | US | disclosed |
| EP-1268525-A2 | MACROCYCLIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS COMPRISING N-CYCLIC P2 MOIETIES | SCHERING CORPORATION (US) | 2003-01-02 | — | — | EP | disclosed |
| US-20020107181-A1 | Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising N-cyclic P2 moieties | SCHERING CORPORATION | 2002-08-08 | — | — | US | disclosed |
| WO-2001077113-A2 | MACROCYCLIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS COMPRISING N-CYCLIC P2 MOIETIES | SCHERING CORPORATION (US) | 2001-10-18 | — | — | WO | disclosed |
| WO-2001064216-A1 | 4-ALKYL PIPERIDINYL PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2001-09-07 | — | — | WO | disclosed |
| EP-0912175-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-09-08 | — | — | EP | disclosed |
| EP-0912175-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998000134-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-01-08 | — | — | WO | disclosed |
| US-4939020-A | Core member for fabrication of shaped plastic | Toyo Coth Co., Ltd. (JP) | 1990-07-03 | — | — | US | disclosed |