Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.58 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.58 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | TEK | Q02763 | 1/20 | 0.57 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.48 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15391257 | 1.00 | EGFR (0.58) | EGFRRIPK2EPHB2KDRTEK | |
| SCHEMBL15390968 | 0.93 | EGFR (0.52) | EGFRRIPK2EPHB2KDRTEK | |
| SCHEMBL26321 | 0.90 | EGFR (0.64) | EGFRKDRERBB2ABCG2HTT | |
| SCHEMBL22983813 | 0.88 | ABCG2 (0.61) | EGFRRIPK2EPHB2KDRTEK | |
| SCHEMBL23406723 | 0.87 | EGFR (0.51) | EGFRRIPK2EPHB2ERBB2ABCG2 | |
| SCHEMBL21835395 | 0.87 | EGFR (0.55) | EGFRRIPK2EPHB2KDRTEK | |
| SCHEMBL15391673 | 0.85 | EGFR (0.74) | EGFRRIPK2EPHB2KDRTEK | |
| SCHEMBL160194 | 0.85 | ABCG2 (0.54) | EGFRABCG2FBP1 | |
| SCHEMBL30638113 | 0.85 | ABCG2 (0.54) | EGFRABCG2FBP1 | |
| SCHEMBL15390935 | 0.84 | FBP1 (0.68) | EGFRRIPK2EPHB2KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079960-A | Alkynyl quinazoline compounds | — | 2026-05-26 | — | — | CN | disclosed |
| CN-119390683-A | Alkynyl quinazoline compounds | 黑钻治疗公司 | 2025-02-07 | — | — | CN | disclosed |