Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30872974 | 0.83 | GRN (0.42) | GRNSORT1BIRC2BACE1MAPK1 | |
| SCHEMBL31276620 | 0.78 | CTSK (0.45) | CTSLCTSSCTSKCYP2C9CYP2C19 | |
| SCHEMBL14533530 | 0.78 | GRN (0.44) | GRNSORT1BACE1MAPK1CTSL | |
| SCHEMBL14211341 | 0.78 | GRN (0.44) | GRNSORT1BACE1MAPK1CTSL | |
| SCHEMBL12514161 | 0.77 | CTSK (0.42) | GRNSORT1BIRC2BACE1MAPK1 | |
| SCHEMBL1361481 | 0.77 | MAPK1 (0.41) | GRNSORT1BACE1MAPK1ALDH1A1 | |
| SCHEMBL28528204 | 0.77 | MAPK1 (0.41) | GRNSORT1BACE1MAPK1ALDH1A1 | |
| SCHEMBL23805193 | 0.77 | CTSK (0.46) | CTSLCTSSCTSKCYP2C9CYP2C19 | |
| SCHEMBL8372342 | 0.77 | CTSK (0.46) | CTSLCTSSCTSKCYP2C9CYP2C19 | |
| SCHEMBL2158515 | 0.77 | CTSK (0.46) | CTSLCTSSCTSKCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403810-A | Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases | 瓦斯塞拉股份有限公司 | 2025-02-07 | — | — | CN | disclosed |