Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31473165 | 0.80 | ITGB3 (0.35) | SMN1; SMN2HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL18926163 | 0.79 | HDAC4 (0.53) | HDAC4HDAC1HDAC6HDAC3HDAC7 | |
| SCHEMBL17896523 | 0.79 | HDAC4 (0.53) | HDAC4HDAC1HDAC6HDAC3HDAC7 | |
| SCHEMBL12228284 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL4402054 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL12228285 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL4405235 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL14952813 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL14952791 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2HDAC4HDAC1HDAC6HDAC3 | |
| SCHEMBL30281500 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2HDAC4HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403810-A | Compounds, pharmaceutical compositions containing them and their medical use for the treatment or prevention of vascular diseases | 瓦斯塞拉股份有限公司 | 2025-02-07 | — | — | CN | disclosed |