SCHEMBL31473173

SCHEMBL31473173

CCCC(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.63
ALDH1A1 P00352 2/20 0.63
NPSR1 Q6W5P4 2/20 0.63
TSHR P16473 2/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
MAPT P10636 2/20 0.63
ABCC3 O15438 1/20 0.63
PLIN1 O60240 1/20 0.63
LMNA P02545 1/20 0.63
TP53 P04637 1/20 0.63
GSTA1 P08263 1/20 0.63
GSTP1 P09211 1/20 0.63
HSPD1 P10809 1/20 0.63
HTT P42858 1/20 0.63
RECQL P46063 1/20 0.63
MAP2K6 P52564 1/20 0.63
HSPE1 P61604 1/20 0.63
GSTO1 P78417 1/20 0.63
PLIN5 Q00G26 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473172 1.00 CYP2C9 (0.63) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL20088746 1.00 CYP2C9 (0.63) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL11601432 0.92 TSHR (0.60) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL11600926 0.89 THRB (0.62) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL9717487 0.87 THRB (0.60) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL9717518 0.86 THRB (0.62) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL10833366 0.85 THRB (0.67) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL9717551 0.85 THRB (0.64) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL9717528 0.83 THRB (0.66) CYP2C9ALDH1A1NPSR1TSHRMEN1
SCHEMBL10001217 0.83 GSTP1 (0.81) CYP2C9ALDH1A1NPSR1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390664-A Crystal form of compound containing alpha, beta unsaturated ketone and preparation method thereof 山东大学 2025-02-07 CN disclosed