Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703994 | 0.81 | KDM1A (0.48) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL18787264 | 0.81 | KDM1A (0.48) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL31473325 | 0.79 | KDM1A (0.46) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL28182366 | 0.79 | KDM1A (0.46) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL9454115 | 0.78 | MRGPRX4 (0.46) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL3168485 | 0.78 | CYP4F2 (0.51) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL31473340 | 0.78 | MEN1 (0.41) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL18787256 | 0.78 | KDM1A (0.45) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL28332769 | 0.77 | KDM1A (0.44) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL17367259 | 0.76 | MAPT (0.53) | KDM1AMAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591604-A | JAK inhibitor compounds and uses thereof | 迈英诺医药科技（珠海）有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2025036296-A1 | JAK INHIBITOR COMPOUND AND USE THEREOF | 迈英诺医药科技（珠海）有限公司 | 2025-02-20 | — | — | WO | disclosed |