Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 10/20 | 0.47 |
| ▸ | JAK3 | P52333 | 9/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | JAK1 | P23458 | 4/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27296079 | 1.00 | CCNA2 (0.47) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL31473394 | 0.92 | JAK2 (0.45) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL27303359 | 0.86 | JAK2 (0.46) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL27309172 | 0.83 | CCNA2 (0.45) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL31473405 | 0.81 | JAK2 (0.44) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL27298649 | 0.81 | JAK2 (0.44) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL27298738 | 0.81 | JAK2 (0.46) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL31473411 | 0.81 | JAK2 (0.46) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL27302585 | 0.81 | JAK2 (0.48) | CCNA2CDK2JAK2JAK3EGLN2 | |
| SCHEMBL27304052 | 0.81 | EGLN2 (0.44) | CCNA2CDK2JAK2JAK3EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119866333-A | KIT inhibitors, compounds, pharmaceutical compositions, and methods of use thereof | 亚力维克希斯股份有限公司 | 2025-04-22 | — | — | CN | disclosed |