Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 10/20 | 0.44 |
| ▸ | JAK3 | P52333 | 9/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 4/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27298649 | 1.00 | JAK2 (0.44) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL27303359 | 0.83 | JAK2 (0.46) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL27296079 | 0.81 | CCNA2 (0.47) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL31473402 | 0.81 | CCNA2 (0.47) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL27306410 | 0.81 | JAK2 (0.47) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL31473466 | 0.81 | JAK2 (0.47) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL27309439 | 0.80 | JAK2 (0.43) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL31473394 | 0.79 | JAK2 (0.45) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL27304976 | 0.79 | JAK2 (0.47) | JAK2JAK3CCNA2CDK2EGLN2 | |
| SCHEMBL31473344 | 0.78 | JAK2 (0.49) | JAK2JAK3CCNA2CDK2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119866333-A | KIT inhibitors, compounds, pharmaceutical compositions, and methods of use thereof | 亚力维克希斯股份有限公司 | 2025-04-22 | — | — | CN | disclosed |