SCHEMBL31473535

SCHEMBL31473535

CC(C)COc1ccc(CC(=O)N(C)[C@H]2CC[C@H](N)CC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 14/20 0.48
CCR5 P51681 3/20 0.47
ACACB O00763 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31473515 0.93 HTR2A (0.47) HTR2ACCR5ACACBSMN1; SMN2
SCHEMBL31473516 0.89 HTR2A (0.47) HTR2ACCR5SMN1; SMN2
SCHEMBL31473504 0.84 CCR5 (0.56) CCR5SMN1; SMN2
SCHEMBL31473529 0.83 HTR2A (0.58) HTR2A
SCHEMBL20795328 0.79 HTR2A (0.51) HTR2ASMN1; SMN2
SCHEMBL20795327 0.79 HTR2A (0.51) HTR2ASMN1; SMN2
SCHEMBL20795329 0.79 HTR2A (0.51) HTR2ASMN1; SMN2
SCHEMBL2405257 0.76 CCR5 (0.62) CCR5SMN1; SMN2
SCHEMBL2404203 0.72 CCR5 (0.65) CCR5
SCHEMBL8987850 0.72 CCR5 (0.54) CCR5SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025061176-A1 CYCLOALKANE-SUBSTITUTED AMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海科技大学 2025-03-27 WO disclosed
CN-119661404-A Cycloalkane substituted amine derivative, preparation method and application thereof 上海科技大学 2025-03-21 CN disclosed