Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 13/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.47 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15241059 | 0.88 | AAK1 (0.50) | AAK1ROCK2CCNCCDK8HASPIN | |
| SCHEMBL19946024 | 0.82 | AAK1 (0.53) | AAK1ROCK2CCNCCDK8HASPIN | |
| SCHEMBL16377274 | 0.78 | ROCK2 (0.70) | AAK1ROCK2CCNCCDK8HASPIN | |
| SCHEMBL18901118 | 0.75 | AAK1 (0.51) | AAK1ROCK2CCNCCDK8HASPIN | |
| SCHEMBL15240307 | 0.73 | AAK1 (0.50) | AAK1ROCK2CCNCCDK8HASPIN | |
| SCHEMBL15973795 | 0.73 | AAK1 (0.53) | AAK1ROCK2CCNCCDK8HASPIN | |
| SCHEMBL10112293 | 0.72 | TNF (0.37) | AAK1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL15973647 | 0.72 | AAK1 (0.52) | AAK1ROCK2CCNCCDK8HASPIN | |
| SCHEMBL21018898 | 0.72 | AAK1 (0.70) | AAK1ROCK2CCNCCDK8HASPIN | |
| SCHEMBL20164880 | 0.70 | AAK1 (1.00) | AAK1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025060978-A1 | TRICYCLIC PYRIDINE COMPOUND ACTING AS SARM1 ENZYME ACTIVITY INHIBITOR, AND USE THEREOF | 科辉智药(深圳)新药研究中心有限公司 | 2025-03-27 | — | — | WO | disclosed |