SCHEMBL31474205

SCHEMBL31474205

CC1(C)Oc2cccc(F)c2O1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.38
ACHE P22303 1/20 0.34
HCAR3 P49019 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
HTR2C P28335 1/20 0.33
HSD17B10 Q99714 1/20 0.31
BACE1 P56817 1/20 0.30
KCNH2 Q12809 1/20 0.30
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10522329 0.81 ALDH1A1 (0.46) ALDH1A1TSHRACHEHTR2CHTR1A
SCHEMBL30677836 0.77 FFAR4 (0.37) ACHEHTR2CBACE1HTR1A
SCHEMBL8976354 0.75 HTR2C (0.33) ACHEHTR2C
SCHEMBL11435846 0.75 ALDH1A1 (0.45) ALDH1A1TSHRHTR1A
SCHEMBL18866953 0.75 ALDH1A1 (0.45) ALDH1A1TSHRSMN1; SMN2HSD17B10KCNH2
SCHEMBL3156898 0.75 ALDH1A1 (0.49) ALDH1A1TSHRHSD17B10KCNH2
SCHEMBL15721688 0.75 ALDH1A1 (0.45) ALDH1A1TSHRHTR1A
SCHEMBL11021936 0.75 AHR (0.45) ALDH1A1TSHRHTR2CHTR1A
SCHEMBL31535480 0.75 FFAR4 (0.41) ALDH1A1SMN1; SMN2HTR2C
SCHEMBL16573103 0.73 ALDH1A1 (0.44) ALDH1A1TSHRHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025061148-A1 HETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE 江苏恒瑞医药股份有限公司 2025-03-27 WO disclosed