Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 13/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.56 |
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | OGA | O60502 | 3/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29215320 | 0.99 | HDAC2 (0.54) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL4092990 | 0.83 | CRBN (0.55) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL2146195 | 0.82 | HDAC2 (0.52) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL4087186 | 0.81 | SCD (0.51) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| Hydrochloric Acid SCHEMBL2828121 | 0.79 | HDAC2 (0.45) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| Hydrochloric Acid SCHEMBL2831916 | 0.79 | HDAC2 (0.45) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL21771311 | 0.79 | SCD (0.55) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL28539361 | 0.77 | HDAC2 (0.47) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL5334339 | 0.77 | OGA (0.55) | HDAC2HDAC3HDAC1HDAC4HDAC7 | |
| SCHEMBL5224561 | 0.76 | HDAC2 (0.76) | HDAC2HDAC3HDAC1HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346573-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | CHENGDU EASTON BIOPHARMACEUTICALS CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| EP-4534533-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Chengdu Easton Biopharmaceuticals Co., Ltd. (CN) | 2025-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346573-A1 | AZAQUINOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | PARP1, PARP8, PARP11 | HDAC2 482/4885HDAC3 1400/4885HDAC1 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.