Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | OGA | O60502 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146195 | 0.86 | HDAC2 (0.52) | SCDHDAC2HDAC3CYP1A2CYP2C18 | |
| SCHEMBL28997099 | 0.81 | SCD (0.51) | SCDHDAC2HDAC3OGAHRH3 | |
| SCHEMBL3131659 | 0.81 | SCD (0.51) | SCDHDAC2HDAC3OGAHRH3 | |
| SCHEMBL16859156 | 0.81 | TDP1 (0.56) | SCDHDAC2HDAC3KCNH2OGA | |
| SCHEMBL28539361 | 0.81 | HDAC2 (0.47) | SCDHDAC2HDAC3CYP1A2CYP2C18 | |
| SCHEMBL4092990 | 0.81 | CRBN (0.55) | HDAC2HDAC3CYP1A2CYP2C18CYP2C19 | |
| SCHEMBL31474329 | 0.81 | HDAC2 (0.56) | SCDHDAC2HDAC3CYP1A2CYP2C18 | |
| SCHEMBL16496524 | 0.80 | SCD (0.59) | SCDHDAC2HDAC3OGAHRH3 | |
| Hydrochloric Acid SCHEMBL29215320 | 0.80 | HDAC2 (0.54) | SCDHDAC2HDAC3CYP1A2CYP2C18 | |
| Hydrochloric Acid SCHEMBL2828121 | 0.80 | HDAC2 (0.45) | SCDHDAC2HDAC3CYP1A2CYP2C18 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099200-A1 | Azacyclohexane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase | MERCK FROSST CANADA LTD. (CA) | 2009-04-16 | — | — | US | disclosed |
| CN-101228156-A | Fungicidal carboxamides | DU PONT (US) | 2008-07-23 | — | — | CN | disclosed |
| EP-1902051-A1 | AZACYCLOHEXANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | Merck Frosst Canada Ltd. (CA) | 2008-03-26 | — | — | EP | disclosed |
| WO-2006130986-A1 | AZACYCLOHEXANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099200-A1 | Azacyclohexane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase | SCD, SCD5, SREBF1 | SCD 1/4885HDAC2 645/4885HDAC3 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.