SCHEMBL31474775

SCHEMBL31474775

NC1=NC(N)(c2ccccc2)NC(N)(c2ccccc2)N1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.40
BACE2 Q9Y5Z0 3/20 0.40
ALDH1A1 P00352 1/20 0.31
KDM1A O60341 6/20 0.31
MAOA P21397 6/20 0.31
MAOB P27338 6/20 0.31
APP P05067 2/20 0.30
REN P00797 1/20 0.30
HTR5A P47898 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31500571 0.72 BACE1 (0.43) BACE1BACE2KDM1AMAOAMAOB
SCHEMBL9718904 0.66 BACE1 (0.37) BACE1BACE2ALDH1A1KDM1AMAOA
SCHEMBL1219239 0.65 MAPK1 (0.36) BACE1BACE2ALDH1A1
SCHEMBL1219238 0.65 RECQL (0.37) BACE1BACE2ALDH1A1HTR5A
SCHEMBL17394336 0.63 HSD17B10 (0.38) BACE1BACE2ALDH1A1
SCHEMBL1172351 0.63 BACE1 (0.38) BACE1BACE2KDM1AMAOAMAOB
SCHEMBL28454137 0.62 BACE1 (0.37) BACE1BACE2KDM1AMAOAMAOB
SCHEMBL28816406 0.60 BACE1 (0.33) BACE1BACE2
SCHEMBL2846013 0.59 BACE1 (0.42) BACE1BACE2MAOAMAOBAPP
SCHEMBL14656128 0.59 BACE1 (0.42) BACE1BACE2MAOAMAOBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119859160-A Functional caprolactam and intrinsic flame-retardant nylon material, and preparation method and application thereof 中国科学院长春应用化学研究所 2025-04-22 CN disclosed
CN-119708470-A Flame-retardant nylon material and preparation method and application thereof 中国科学院长春应用化学研究所 2025-03-28 CN disclosed