Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 6/20 | 0.32 |
| ▸ | MAOA | P21397 | 6/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107125 | 0.77 | KDM1A (0.42) | BACE1BACE2KDM1APNMT | |
| SCHEMBL2846014 | 0.67 | BACE1 (0.37) | BACE1BACE2ALDH1A1KDM1AMAOA | |
| SCHEMBL31474775 | 0.66 | BACE1 (0.40) | BACE1BACE2ALDH1A1KDM1AMAOA | |
| SCHEMBL31500571 | 0.65 | BACE1 (0.43) | BACE1BACE2KDM1AMAOAMAOB | |
| SCHEMBL15757326 | 0.63 | BACE1 (0.37) | BACE1BACE2ALDH1A1 | |
| SCHEMBL30764023 | 0.61 | GRM4 (0.33) | BACE1BACE2ALDH1A1MAOAMAOB | |
| SCHEMBL10763454 | 0.60 | MAOA (0.33) | BACE1BACE2KDM1AMAOAMAOB | |
| SCHEMBL2764061 | 0.60 | NPY5R (0.37) | ALDH1A1 | |
| SCHEMBL1172351 | 0.60 | BACE1 (0.38) | BACE1BACE2KDM1AMAOAMAOB | |
| SCHEMBL10650069 | 0.60 | PNMT (0.34) | KDM1AMAOAMAOBPNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112926-A | Improved hardness, toughness and drilling properties | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1992-05-12 | — | — | US | disclosed |
| US-3839332-A | PROCESS FOR THE MANUFACTURE OF ANTHRAQUINONE DYESTUFFS | CIBA GEIGY AG | 1974-10-01 | — | — | US | disclosed |