SCHEMBL31475161 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	KDR	P35968	4/20	0.34

▸	PLK4	O00444	2/20	0.34

▸	AURKA	O14965	2/20	0.34

▸	MAP4K4	O95819	2/20	0.34

▸	PAK4	O96013	2/20	0.34

▸	ABL1	P00519	2/20	0.34

▸	LCK	P06239	2/20	0.34

▸	CSF1R	P07333	2/20	0.34

▸	RET	P07949	2/20	0.34

▸	MET	P08581	2/20	0.34

▸	PDGFRB	P09619	2/20	0.34

▸	KIT	P10721	2/20	0.34

▸	FGFR1	P11362	2/20	0.34

▸	PDGFRA	P16234	2/20	0.34

▸	FLT1	P17948	2/20	0.34

▸	FGFR3	P22607	2/20	0.34

▸	TYK2	P29597	2/20	0.34

▸	AXL	P30530	2/20	0.34

▸	FLT4	P35916	2/20	0.34

▸	BLK	P51451	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31475194	0.95	KDR (0.34)	KDRPLK4AURKAMAP4K4PAK4
SCHEMBL31475212	0.94	KDR (0.37)	KDRTTK
SCHEMBL30786214	0.91	KDR (0.34)	KDR
SCHEMBL31475185	0.90	KDR (0.34)	KDRPLK4AURKAMAP4K4PAK4
SCHEMBL30786216	0.90	KDR (0.37)	KDRTTK
SCHEMBL30786086	0.89	KDR (0.32)	KDRPLK4AURKAMAP4K4PAK4
SCHEMBL31475215	0.88	KDR (0.37)	KDRTTK
SCHEMBL31475172	0.87	GPR119 (0.32)	RXRARXRBRXRG
SCHEMBL31475199	0.85	KDR (0.34)	KDRPLK4AURKAMAP4K4PAK4
SCHEMBL31475207	0.84	KDR (0.36)	KDRTTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-119604488-A	Protein tyrosine kinase inhibitor and medical application thereof	苏州必扬医药科技有限公司	2025-03-11	—	—	CN	disclosed