Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 13/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.36 |
| ▸ | PLK4 | O00444 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | PAK4 | O96013 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 2/20 | 0.35 |
| ▸ | FLT4 | P35916 | 2/20 | 0.35 |
| ▸ | BLK | P51451 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786173 | 0.90 | KDR (0.44) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL31475317 | 0.90 | KDR (0.47) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL30786112 | 0.90 | KDR (0.44) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL30786229 | 0.90 | KDR (0.44) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL30786074 | 0.86 | KDR (0.45) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL31475189 | 0.86 | KDR (0.46) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL31475200 | 0.85 | KDR (0.46) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL31475183 | 0.83 | KDR (0.46) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL30786084 | 0.82 | KDR (0.44) | KDRFGFR1PLK4AURKAMAP4K4 | |
| SCHEMBL30786222 | 0.82 | KDR (0.68) | KDRFGFR1PLK4AURKAMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082316-A1 | OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州必扬医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |