Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | PAK4 | O96013 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786229 | 0.99 | KDR (0.44) | KDRFGFR1BMPR1BHTR7BMPR1A | |
| SCHEMBL30786112 | 0.91 | KDR (0.44) | KDRFGFR1BMPR1BDRD2PLK4 | |
| SCHEMBL30786084 | 0.90 | KDR (0.44) | KDRFGFR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL31475192 | 0.90 | KDR (0.45) | KDRFGFR1BMPR1BPLK4AURKA | |
| SCHEMBL31475200 | 0.90 | KDR (0.46) | KDRFGFR1BMPR1BPLK4AURKA | |
| SCHEMBL30786182 | 0.85 | KDR (0.41) | KDRFGFR1BMPR1BPLK4AURKA | |
| SCHEMBL31475183 | 0.85 | KDR (0.46) | KDRFGFR1BMPR1BPLK4AURKA | |
| SCHEMBL31475317 | 0.85 | KDR (0.47) | KDRFGFR1BMPR1BPLK4AURKA | |
| SCHEMBL31475189 | 0.84 | KDR (0.46) | KDRFGFR1BMPR1BPLK4AURKA | |
| SCHEMBL30786074 | 0.82 | KDR (0.45) | KDRFGFR1BMPR1BPLK4AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082316-A1 | OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州必扬医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| CN-119604488-A | Protein tyrosine kinase inhibitor and medical application thereof | 苏州必扬医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |