Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328140 | 1.00 | TSHR (0.38) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL6696572 | 1.00 | TSHR (0.38) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL9436918 | 1.00 | TSHR (0.38) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL3797094 | 0.97 | TSHR (0.39) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL523644 | 0.89 | — | — | |
| SCHEMBL2101357 | 0.77 | — | — | |
| SCHEMBL3418812 | 0.77 | TSHR (0.42) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL12677768 | 0.77 | TSHR (0.42) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL1004438 | 0.76 | ALDH1A1 (0.58) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL645518 | 0.76 | ALDH1A1 (0.58) | TSHRALDH1A1TDP1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2191883-B1 | Porous hybrid particles with organic groups removed from surface | WATERS TECHNOLOGIES CORP (US) | 2013-08-28 | — | — | EP | disclosed |
| EP-2191883-A1 | Porous hybrid particles with organic groups removed from surface | Waters Technologies Corporation (US) | 2010-06-02 | — | — | EP | disclosed |
| EP-1361915-B1 | METHOD OF PREPARING OF POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE | WATERS TECHNOLOGIES CORP (US) | 2010-03-03 | — | — | EP | disclosed |
| EP-1361915-A4 | POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE | WATERS INVESTMENTS LTD (US) | 2006-10-04 | — | — | EP | disclosed |
| EP-1361915-A1 | POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE | Waters Investments Limited (US) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002060562-A1 | POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE | WATERS INVESTMENTS LIMITED (US) | 2002-08-08 | — | — | WO | disclosed |