Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 19/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 1/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 1/20 | 1.00 |
| ▸ | CTSG | P08311 | 1/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404228 | 1.00 | CMA1 (1.00) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL23752344 | 1.00 | CMA1 (1.00) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL1001215 | 0.92 | CMA1 (1.00) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL406708 | 0.91 | CMA1 (1.00) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL999324 | 0.90 | CMA1 (1.00) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL3708588 | 0.90 | CMA1 (0.81) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL408281 | 0.88 | CMA1 (0.79) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL3654773 | 0.88 | CMA1 (1.00) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL998105 | 0.87 | CMA1 (0.78) | CMA1PRSS1PRSS2CTSGPRSS3 | |
| SCHEMBL13009082 | 0.87 | CMA1 (0.78) | CMA1PRSS1PRSS2CTSGPRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127908-A1 | HETEROBIFUNCTIONAL CONDITIONAL INHIBITORS | KOLM THERAPEUTICS INC. | 2025-04-24 | — | — | US | claimed |
| WO-2025081091-A1 | HETEROBIFUNCTIONAL CONDITIONAL INHIBITORS | KOLM THERAPEUTICS INC. (US) | 2025-04-17 | — | — | WO | claimed |
| US-20250127908-A1 | HETEROBIFUNCTIONAL CONDITIONAL INHIBITORS | KOLM THERAPEUTICS INC. | 2025-04-24 | — | — | US | disclosed |
| WO-2025081091-A1 | HETEROBIFUNCTIONAL CONDITIONAL INHIBITORS | KOLM THERAPEUTICS INC. (US) | 2025-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127908-A1 | HETEROBIFUNCTIONAL CONDITIONAL INHIBITORS | BRDT, NFKBIA, SSB | CMA1 2104/4885PRSS1 1505/4885PRSS2 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.