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Sugi Predict / Compounds / SCHEMBL23752344

SCHEMBL23752344

SCHEMBL23752344

O=C(Nc1ccc2ccccc2c1)[C@H](c1csc2ccc(Cl)cc12)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CMA1 P23946 19/20 1.00
▸ PRSS1 P07477 1/20 1.00
▸ PRSS2 P07478 1/20 1.00
▸ CTSG P08311 1/20 1.00
▸ PRSS3 P35030 1/20 1.00
▸ KDM4E B2RXH2 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31476750 1.00 CMA1 (1.00) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL404228 1.00 CMA1 (1.00) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL1001215 0.92 CMA1 (1.00) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL406708 0.91 CMA1 (1.00) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL999324 0.90 CMA1 (1.00) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL3708588 0.90 CMA1 (0.81) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL408281 0.88 CMA1 (0.79) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL3654773 0.88 CMA1 (1.00) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL998105 0.87 CMA1 (0.78) CMA1PRSS1PRSS2CTSGPRSS3
SCHEMBL13009082 0.87 CMA1 (0.78) CMA1PRSS1PRSS2CTSGPRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 — — US disclosed