Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 6/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920680 | 0.94 | KDM1A (0.43) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL691736 | 0.84 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL31088903 | 0.83 | PRKDC (0.38) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL1517367 | 0.83 | PRKDC (0.38) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL29655114 | 0.80 | ERN1 (0.43) | ERN1PRKDCKDM1AKDM1BLMNA | |
| SCHEMBL933374 | 0.80 | ERN1 (0.43) | ERN1PRKDCKDM1AKDM1BLMNA | |
| SCHEMBL548760 | 0.80 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4ERN1 | |
| SCHEMBL633623 | 0.78 | ERN1 (0.45) | ERN1PRKDCKDM1AKDM1BLMNA | |
| SCHEMBL18479925 | 0.78 | KDM1A (0.37) | KDM1AKDM1B | |
| SCHEMBL20140233 | 0.78 | LMNA (0.42) | ERN1PRKDCKDM1AALDH1A1KDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |