Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28939224 | 1.00 | BRD4 (0.40) | BRD4ARCHEK1NAMPTGRM2 | |
| SCHEMBL3049208 | 0.83 | ALDH1A1 (0.40) | BRD4ARCHEK1NAMPTGRM2 | |
| SCHEMBL453184 | 0.80 | BRD4 (0.39) | BRD4ARCHEK1NAMPTGRM2 | |
| SCHEMBL2643631 | 0.80 | BRD4 (0.36) | BRD4ARCHEK1NAMPTGRM2 | |
| SCHEMBL5498500 | 0.76 | TP53 (0.45) | BRD4ARCHEK1NAMPTGRM2 | |
| SCHEMBL24146512 | 0.76 | GAA (0.38) | BRD4ARCHEK1NAMPTGRM2 | |
| SCHEMBL453185 | 0.76 | CHEK1 (0.44) | BRD4ARCHEK1NAMPTGRM2 | |
| SCHEMBL450834 | 0.76 | ALDH1A1 (0.42) | ARCHEK1KCNQ3KCNQ2EGLN2 | |
| SCHEMBL452013 | 0.76 | BRD4 (0.36) | BRD4ARCHEK1NAMPTGRM2 | |
| SCHEMBL507109 | 0.76 | AR (0.41) | BRD4ARCHEK1NAMPTGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085554-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |