Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1166933 | 1.00 | KMT2A (0.58) | KMT2AADRA2CADRA2ALMNAHIF1A | |
| SCHEMBL2502288 | 1.00 | KMT2A (0.58) | KMT2AADRA2CADRA2ALMNAHIF1A | |
| SCHEMBL8229829 | 1.00 | KMT2A (0.58) | KMT2AADRA2CADRA2ALMNAHIF1A | |
| Hydrochloric Acid SCHEMBL31477615 | 0.98 | KMT2A (0.56) | KMT2AADRA2CADRA2ALMNAHIF1A | |
| Hydrochloric Acid SCHEMBL11337319 | 0.98 | KMT2A (0.56) | KMT2AADRA2CADRA2ALMNAHIF1A | |
| Hydrochloric Acid SCHEMBL16295385 | 0.98 | KMT2A (0.56) | KMT2AADRA2CADRA2ALMNAHIF1A | |
| SCHEMBL14569757 | 0.84 | ACHE (0.44) | KMT2ALMNAALDH1A1ACHEADRA1A | |
| SCHEMBL17065349 | 0.83 | KMT2A (0.60) | KMT2ALMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL28111441 | 0.83 | KMT2A (0.60) | KMT2ALMNAALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL16228151 | 0.82 | AOC3 (0.47) | KMT2ACYP2D6CYP1A2ACHEAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085564-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025085554-A1 | LYSINE ACETYLTRANSFERASE INHIBITORS | Kronos Bio, Inc. (US) | 2025-04-24 | — | — | WO | disclosed |