Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29283681 | 0.75 | AKT1 (0.54) | HPGDMEN1KMT2A | |
| SCHEMBL2187602 | 0.75 | HPGD (1.00) | HPGDHDAC3GAAKDM4EHDAC2 | |
| SCHEMBL14563856 | 0.75 | TMEM97 (0.51) | HDAC3HDAC2HDAC8HDAC1MEN1 | |
| SCHEMBL8133786 | 0.74 | HDAC2 (0.61) | HPGDHDAC3GAAKDM4EHDAC2 | |
| SCHEMBL5933901 | 0.74 | HPGD (0.97) | HPGDHDAC3GAAKDM4EHDAC2 | |
| SCHEMBL13287459 | 0.74 | HPGD (0.97) | HPGDHDAC3GAAKDM4EHDAC2 | |
| SCHEMBL1093862 | 0.73 | HPGD (0.91) | HPGDHDAC3GAAKDM4EHDAC2 | |
| SCHEMBL12040742 | 0.72 | KMT2A (0.62) | HPGDHDAC3EPHX2KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL8586995 | 0.71 | EPHX2 (0.56) | HPGDHDAC3HDAC2HDAC8EPHX2 | |
| SCHEMBL21454929 | 0.71 | HDAC3 (1.00) | HPGDHDAC3GAAKDM4ECRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051124-A1 | AURISTATIN F ANALOGUE, ANTIBODY DRUG CONJUGATE AND USE THEREOF | 诺灵生物医药科技(北京)有限公司 | 2025-03-13 | — | — | WO | disclosed |