SCHEMBL31478948

SCHEMBL31478948

CC(C)[C@@H](CN1CC[C@H](O)C1)N(C)C(=O)c1cc(F)cc(C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 6/20 0.43
▸ CYP2D6 P10635 3/20 0.43
▸ HRH3 Q9Y5N1 1/20 0.39
▸ OPRM1 P35372 2/20 0.39
▸ OPRD1 P41143 2/20 0.39
▸ UBE2M P61081 3/20 0.38
▸ DCUN1D1 Q96GG9 3/20 0.38
▸ BDKRB1 P46663 2/20 0.37
▸ CCR2 P41597 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9101607 1.00 OPRK1 (0.43) OPRK1CYP2D6HRH3OPRM1OPRD1
SCHEMBL9104308 0.86 TACR2 (0.41) OPRK1CYP2D6
SCHEMBL31478933 0.86 TACR2 (0.41) OPRK1CYP2D6
SCHEMBL9104300 0.86 TACR2 (0.41) OPRK1CYP2D6
SCHEMBL9104502 0.82 HRH3 (0.44) OPRK1CYP2D6HRH3OPRM1OPRD1
SCHEMBL9104486 0.82 HRH3 (0.44) OPRK1CYP2D6HRH3OPRM1OPRD1
SCHEMBL9106114 0.80 SMO (0.41) OPRK1CYP2D6OPRM1OPRD1
SCHEMBL9106105 0.80 SMO (0.41) OPRK1CYP2D6OPRM1OPRD1
SCHEMBL9102911 0.78 HRH3 (0.44) OPRK1CYP2D6HRH3OPRM1OPRD1
SCHEMBL9101346 0.78 HRH3 (0.44) OPRK1CYP2D6HRH3OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025082731-A1 INTRANASAL FORMULATIONS FOR TREATING OBSTRUCTIVE SLEEP APNEA MOSANNA THERAPEUTICS AG (CH) 2025-04-24 — — WO disclosed
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