SCHEMBL31479025

SCHEMBL31479025

CCS(=O)(=O)NC1CCC(CN2CC(c3cc(-c4ccc(F)cc4C(=O)N(CC(F)F)C(C)C)c4cnn(C)c4c3)C2)CC1

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KCNH2 Q12809 1/20 0.43
HTR2A P28223 1/20 0.36
DRD3 P35462 1/20 0.36
TRPV1 Q8NER1 1/20 0.33
LIPG Q9Y5X9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479726 0.94 MEN1 (0.43) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479305 0.91 MEN1 (0.43) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479326 0.91 MEN1 (0.36) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479895 0.90 KCNH2 (0.49) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479563 0.88 MEN1 (0.43) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479475 0.88 MEN1 (0.43) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479220 0.88 MEN1 (0.43) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479490 0.87 KCNH2 (0.36) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31479557 0.87 KCNH2 (0.36) MEN1KMT2AKCNH2HTR2ADRD3
SCHEMBL31478972 0.81 SSTR4 (0.33) KCNH2HTR2ATRPV1LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 WO disclosed