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SCHEMBL31479895

SCHEMBL31479895

CCN(C(=O)c1cc(F)ccc1-c1cc(C2CCN(CC3CCC(NS(=O)(=O)CC)CC3)C2)cc2c1cnn2C)C(C)C

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 5/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ HTR2A P28223 13/20 0.40
▸ DRD3 P35462 6/20 0.40
▸ ACKR3 P25106 3/20 0.34
▸ HTR7 P34969 6/20 0.33
▸ DRD2 P14416 5/20 0.33
▸ TRPV1 Q8NER1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479726 0.91 MEN1 (0.43) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31479025 0.90 MEN1 (0.43) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31479440 0.89 KCNH2 (0.42) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31479214 0.89 KCNH2 (0.42) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31479046 0.89 KCNH2 (0.42) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31478977 0.88 KCNH2 (0.49) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31479313 0.88 KCNH2 (0.49) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31479210 0.88 KCNH2 (0.49) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31479645 0.85 MEN1 (0.51) KCNH2MEN1KMT2AHTR2ADRD3
SCHEMBL31479610 0.85 MEN1 (0.51) KCNH2MEN1KMT2AHTR2ADRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 — — WO disclosed