Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 7/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479281 | 1.00 | MEN1 (0.41) | MEN1KMT2AKCNH2DRD2JAK2 | |
| SCHEMBL31478964 | 1.00 | MEN1 (0.41) | MEN1KMT2AKCNH2DRD2JAK2 | |
| SCHEMBL31479276 | 0.88 | MEN1 (0.51) | MEN1KMT2AKCNH2ACKR3HTR2A | |
| SCHEMBL31479432 | 0.88 | MEN1 (0.51) | MEN1KMT2AKCNH2ACKR3HTR2A | |
| SCHEMBL31479775 | 0.88 | MEN1 (0.51) | MEN1KMT2AKCNH2ACKR3HTR2A | |
| SCHEMBL31479556 | 0.87 | KCNH2 (0.39) | MEN1KMT2AKCNH2DRD2ACKR3 | |
| SCHEMBL31479396 | 0.87 | KCNH2 (0.39) | MEN1KMT2AKCNH2DRD2ACKR3 | |
| SCHEMBL31479036 | 0.87 | KCNH2 (0.39) | MEN1KMT2AKCNH2DRD2ACKR3 | |
| SCHEMBL31479439 | 0.84 | GPR119 (0.38) | — | |
| SCHEMBL31479677 | 0.84 | GPR119 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |