SCHEMBL31479181 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	EPHX2	P34913	1/20	0.40

▸	KDM4E	B2RXH2	1/20	0.40

▸	TP53	P04637	1/20	0.38

▸	SMN1; SMN2	Q16637	3/20	0.36

▸	MEN1	O00255	1/20	0.36

▸	KMT2A	Q03164	1/20	0.36

▸	ALDH1A1	P00352	2/20	0.35

▸	POLB	P06746	1/20	0.34

▸	GAA	P10253	1/20	0.34

▸	LMNA	P02545	1/20	0.34

▸	IDO1	P14902	1/20	0.34

▸	MAPT	P10636	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15656431	0.76	EPHX2 (0.46)	EPHX2POLBLMNA
SCHEMBL29159598	0.75	EPHX2 (0.41)	EPHX2KDM4ETP53SMN1; SMN2MEN1
SCHEMBL22228077	0.72	SMN1; SMN2 (0.41)	KDM4ETP53SMN1; SMN2MEN1KMT2A
SCHEMBL22228075	0.72	SMN1; SMN2 (0.41)	KDM4ETP53SMN1; SMN2MEN1KMT2A
SCHEMBL16793947	0.72	KDM5A (0.41)	KDM4ETP53SMN1; SMN2MEN1KMT2A
SCHEMBL24669915	0.72	KDM5A (0.41)	KDM4ETP53SMN1; SMN2MEN1KMT2A
SCHEMBL30642227	0.72	JAK1 (0.45)	EPHX2KMT2A
SCHEMBL244740	0.71	—	—
SCHEMBL2948892	0.71	TP53 (0.56)	TP53SMN1; SMN2ALDH1A1POLBGAA
SCHEMBL2200767	0.71	TP53 (0.56)	TP53SMN1; SMN2ALDH1A1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025067111-A1	MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION	苏州必扬医药科技有限公司	2025-04-03	—	—	WO	disclosed