SCHEMBL2200767

SCHEMBL2200767

COC(=O)[C@H]1CC[C@@H](C(=O)OC)CC1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.52
CHRNB2 P17787 2/20 0.50
CHRNA4 P43681 2/20 0.50
CHRNB4 P30926 1/20 0.50
CHRNA3 P32297 1/20 0.50
CHRNA7 P36544 1/20 0.50
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
PPM1B O75688 1/20 0.46
PTPN1 P18031 1/20 0.46
PPP1CC P36873 1/20 0.46
BRD4 O60885 1/20 0.45
ALDH1A1 P00352 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2948892 1.00 TP53 (0.56) TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4
SCHEMBL244740 1.00
SCHEMBL74396 1.00 TP53 (0.56) TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4
Methyl Alcohol SCHEMBL27845135 0.97 TP53 (0.54) TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4
Hydrochloric Acid SCHEMBL6271997 0.97
SCHEMBL8610883 0.97 TP53 (0.54) TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4
Ethylene SCHEMBL27716391 0.94
Ethylene SCHEMBL11226332 0.94 TP53 (0.52) TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4
SCHEMBL10681039 0.92 TP53 (0.50) TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4
SCHEMBL4547605 0.92 TP53 (0.55) TP53SMN1; SMN2CHRNB2CHRNA4CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836383-A Polyamide copolymer with regular chain segment structure and preparation method thereof 北京化工大学 2023-10-03 CN claimed
US-8299292-B2 Method of preparing of 60% or more CIS-DI(C4-C20)alkyl cyclohexane-1,4-dicarboxylate HANWHA CHEMICAL CORPORATION (KR) 2012-10-30 US claimed
US-20110263770-A1 Method of Preparing of 60% or More CIS-DI(C4-C20)Alkyl Cyclohexane-1,4-Dicarboxylate HANWHA CHEMICAL CORPORATION (KR) 2011-10-27 US claimed
EP-2344443-A2 METHOD OF PREPARING OF 60% OR MORE CIS-DI(C4-C20)ALKYL CYCLOHEXANE-1,4-DICARBOXYLATE Hanwha Chemical Corporation (KR) 2011-07-20 EP claimed
WO-2010044638-A2 METHOD OF PREPARING OF 60% OR MORE CIS-DI(C4-C20)ALKYL CYCLOHEXANE-1,4-DICARBOXYLATE HANWHA CHEMICAL CORPORATION (KR) 2010-04-22 WO claimed
EP-0656339-B1 Process for the production of cyclohexanedimethanol, with preponderance of the trans-isomer EASTMAN CHEM CO (US) 1998-04-22 EP claimed
EP-0656334-B1 Process for the production of cyclohexanedimethanol, with preponderance of the trans-isomer EASTMAN CHEM CO (US) 1998-04-22 EP claimed
EP-0656341-B1 Process for the production of cyclohexanedimethanol EASTMAN CHEM CO (US) 1998-04-22 EP claimed
EP-0656337-B1 Process for the production of 1,4-cyclohexanedimethanol EASTMAN CHEM CO (US) 1997-07-30 EP claimed
EP-0656337-A1 Process for the production of 1,4-cydohexanedimethanol EASTMAN CHEMICAL COMPANY (US) 1995-06-07 EP claimed
EP-0656334-A1 Process for the production of cydohexanedimethanol, with preponderance of the trans-isomer EASTMAN CHEMICAL COMPANY (US) 1995-06-07 EP claimed
EP-0656339-A1 Process for the production of cydohexanedimethanol, with preponderance of the trans-isomer EASTMAN CHEMICAL COMPANY (US) 1995-06-07 EP claimed
EP-0656341-A1 Process for the production of cydohexanedimethanol EASTMAN CHEMICAL COMPANY (US) 1995-06-07 EP claimed
US-5414159-A Hydrogenation of dialkyl cyclohexanedicarboxylate to form cyclohexanedimethanol EASTMAN CHEMICAL COMPANY (US) 1995-05-09 US claimed
US-5395987-A Hydrogenation of ester EASTMAN CHEMICAL COMPANY (US) 1995-03-07 US claimed
US-5395986-A Hydrogenation of dialkyl cyclohexanedicarboxylate using copper or group VIII compound catalysts; high trans configuration to cis ratio EASTMAN CHEMICAL COMPANY (US) 1995-03-07 US claimed
US-5387752-A Catalytic hydrogenation of a dialkylcyclohexanedicarboxylate EASTMAN CHEMICAL COMPANY (US) 1995-02-07 US claimed
EP-3530690-B1 PLASTICIZER COMPOSITION COMPRISING CYCLOHEXANE 1,4-DIESTER-BASED COMPOUND, AND RESIN COMPOSITION COMPRISING SAME LG CHEMICAL LTD (KR) 2025-10-29 EP disclosed
US-5387753-A Catalytic hydrogenating vapor stream unsaturated esters, diesters or lactones in presence of coppor containing catalyst , reactivating the copper catalyst by a stream of hydrogen gas free of reactants EASTMAN CHEMICAL COMPANY (US) 1995-02-07 US disclosed
US-4024173-A Process for the manufacture of cyclohexene dicarboxylic acid esters DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263770-A1 Method of Preparing of 60% or More CIS-DI(C4-C20)Alkyl Cyclohexane-1,4-Dicarboxylate ADH1A, ADH1C, DDT TP53 2403/4885SMN1; SMN2 3932/4885CHRNB2 3885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.