SCHEMBL31479182

SCHEMBL31479182

CCN(C(=O)c1cc(F)ccc1-c1cc(C2CN([C@H](CCCN3CCC(NS(=O)(=O)CC)CC3)C(C)C)C2)cn2c(C)ncc12)C(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 6/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HTR7 P34969 11/20 0.33
HTR1A P08908 3/20 0.33
HTR2A P28223 12/20 0.32
DRD2 P14416 7/20 0.32
DRD3 P35462 1/20 0.32
HTR6 P50406 2/20 0.31
ADRA1D P25100 1/20 0.30
ADRA1A P35348 1/20 0.30
ADRA1B P35368 1/20 0.30
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30
CCR5 P51681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479582 0.91 HTR2A (0.34) KCNH2MEN1KMT2AHTR7HTR2A
SCHEMBL31479047 0.90 HCRTR1 (0.33) KCNH2MEN1KMT2AHTR7HTR2A
SCHEMBL31479356 0.90 HCRTR1 (0.33) KCNH2MEN1KMT2AHTR7HTR2A
SCHEMBL31479224 0.90 HTR2A (0.33) KCNH2MEN1KMT2AHTR7HTR2A
SCHEMBL31479408 0.89 HTR2A (0.32) KCNH2MEN1KMT2AHTR7HTR2A
SCHEMBL31479507 0.89 HTR2A (0.32) KCNH2MEN1KMT2AHTR7HTR2A
SCHEMBL31479435 0.89 HTR2A (0.32) KCNH2MEN1KMT2AHTR7HTR2A
SCHEMBL31479091 0.89 HTR2A (0.33) KCNH2HTR7HTR2ADRD2HCRTR1
SCHEMBL31479577 0.88 DRD2 (0.31) MEN1KMT2AHTR7HTR2ADRD2
SCHEMBL31479215 0.88 DRD2 (0.31) MEN1KMT2AHTR7HTR2ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 WO disclosed