Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479235 | 1.00 | PLK1 (0.34) | PLK1GPR119GPBAR1IDO1TDO2 | |
| SCHEMBL31479175 | 0.90 | HCRTR1 (0.34) | MAPK14 | |
| SCHEMBL31479721 | 0.90 | HCRTR1 (0.34) | MAPK14 | |
| SCHEMBL31479002 | 0.90 | HTR2A (0.32) | MAPK14 | |
| SCHEMBL31479316 | 0.89 | HTR2A (0.34) | — | |
| SCHEMBL31479627 | 0.89 | HTR2A (0.34) | — | |
| SCHEMBL31479852 | 0.89 | GPBAR1 (0.40) | PLK1GPR119GPBAR1SMN1; SMN2TP53 | |
| SCHEMBL31479636 | 0.88 | HTR2A (0.32) | MAPK14 | |
| SCHEMBL31479576 | 0.88 | HTR2A (0.32) | MAPK14 | |
| SCHEMBL31479320 | 0.86 | GPR119 (0.39) | GPR119GPBAR1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |