SCHEMBL31479810

SCHEMBL31479810

CON(C)C(=O)CC[C@@H]1CN(C(=O)OC(C)(C)C)CCO1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RECQL P46063 1/20 0.38
EPHA2 P29317 4/20 0.38
PDK1 Q15118 3/20 0.37
ERBB2 P04626 1/20 0.36
EPHB4 P54760 1/20 0.36
ENPP2 Q13822 2/20 0.35
USP30 Q70CQ3 1/20 0.35
NR1H2 P55055 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
JAK2 O60674 1/20 0.34
JAK1 P23458 1/20 0.34
GPR119 Q8TDV5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764578 1.00 USP2 (0.42) USP2SMN1; SMN2RECQLEPHA2PDK1
SCHEMBL23764579 1.00 USP2 (0.42) USP2SMN1; SMN2RECQLEPHA2PDK1
SCHEMBL29750633 0.84 PDK1 (0.41) PDK1ENPP2
SCHEMBL28795321 0.84 PDK1 (0.41) PDK1ENPP2
SCHEMBL28795422 0.83 USP2 (0.46) USP2SMN1; SMN2RECQLEPHA2PDK1
SCHEMBL28795423 0.83 USP2 (0.46) USP2SMN1; SMN2RECQLEPHA2PDK1
SCHEMBL29022353 0.83 USP2 (0.46) USP2SMN1; SMN2RECQLEPHA2PDK1
SCHEMBL31479278 0.83 USP2 (0.48) USP2SMN1; SMN2RECQLEPHA2PDK1
SCHEMBL18259593 0.83 USP2 (0.48) USP2SMN1; SMN2RECQLEPHA2PDK1
SCHEMBL18259594 0.83 USP2 (0.48) USP2SMN1; SMN2RECQLEPHA2PDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 WO disclosed