Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479237 | 0.94 | POLB (0.45) | POLBTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31479407 | 0.94 | POLB (0.45) | POLBTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31479184 | 0.94 | POLB (0.45) | POLBTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31479687 | 0.90 | SMN1; SMN2 (0.42) | POLBTP53SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31479350 | 0.87 | ALDH1A1 (0.41) | POLBTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31479762 | 0.86 | GPBAR1 (0.40) | POLBTP53SMN1; SMN2GPBAR1GPR119 | |
| SCHEMBL31479892 | 0.86 | GPBAR1 (0.38) | POLBSMN1; SMN2GPBAR1GPR119ALOX5AP | |
| SCHEMBL31479060 | 0.85 | TP53 (0.40) | POLBTP53ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL31479132 | 0.85 | GPBAR1 (0.41) | POLBSMN1; SMN2GPBAR1GPR119ALOX5AP | |
| SCHEMBL31479001 | 0.84 | TSHR (0.36) | ALDH1A1SMN1; SMN2MEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |