Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 6/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479296 | 0.92 | HCRTR1 (0.36) | ACVR1HDAC3BMPR1BTGFBR1ACVRL1 | |
| SCHEMBL31479662 | 0.90 | HCRTR1 (0.35) | ACVR1HDAC3BMPR1BTGFBR1ACVRL1 | |
| SCHEMBL31479471 | 0.87 | SLC6A2 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL31479700 | 0.86 | RET (0.37) | — | |
| SCHEMBL31479391 | 0.85 | MEN1 (0.41) | — | |
| SCHEMBL31479476 | 0.85 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL31479725 | 0.85 | HCRTR1 (0.36) | ALKACVR1HDAC3BMPR1BTGFBR1 | |
| SCHEMBL31479179 | 0.85 | HDAC3 (0.34) | ALKACVR1HDAC3BMPR1BTGFBR1 | |
| SCHEMBL31479580 | 0.84 | SLC6A2 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL31479031 | 0.83 | GRIN2B (0.35) | TGFBR1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |