Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 7/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 7/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479662 | 0.98 | HCRTR1 (0.35) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31479880 | 0.92 | ALK (0.34) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31479725 | 0.91 | HCRTR1 (0.36) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31479756 | 0.89 | HCRTR1 (0.36) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31478986 | 0.88 | MEN1 (0.36) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479294 | 0.87 | HCRTR1 (0.36) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479179 | 0.86 | HDAC3 (0.34) | ACVR1BMPR1BTGFBR1ACVRL1HDAC3 | |
| SCHEMBL31478997 | 0.85 | HCRTR1 (0.36) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31479368 | 0.85 | HCRTR1 (0.34) | HCRTR1HCRTR2ACVR1BMPR1BKDR | |
| SCHEMBL31479417 | 0.84 | HCRTR1 (0.37) | HCRTR1HCRTR2TGFBR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |