Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749249 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL20552373 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL1967730 | 0.92 | PRMT5 (0.44) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL1975644 | 0.92 | PRMT5 (0.44) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL1980890 | 0.92 | PRMT5 (0.44) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL27406227 | 0.87 | MEN1 (0.49) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL16993101 | 0.87 | MEN1 (0.49) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL20120311 | 0.87 | NR1H2 (0.46) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL5664877 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTPRMT5 | |
| SCHEMBL5664868 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPTPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |