Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 2/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479478 | 0.94 | HCRTR1 (0.37) | HCRTR1HCRTR2BRD4BRD2BRD3 | |
| SCHEMBL31478944 | 0.87 | HCRTR1 (0.35) | HCRTR1HCRTR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31479254 | 0.84 | GPBAR1 (0.38) | HCRTR1HCRTR2BRD4BRD3 | |
| SCHEMBL31479501 | 0.83 | HCRTR1 (0.35) | HCRTR1HCRTR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31479082 | 0.83 | GPR119 (0.40) | BRD4BRD3 | |
| SCHEMBL31479746 | 0.80 | SLC6A2 (0.35) | HCRTR1HCRTR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31479165 | 0.80 | SLC6A2 (0.35) | HCRTR1HCRTR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31479159 | 0.80 | SLC6A2 (0.35) | HCRTR1HCRTR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31479417 | 0.80 | HCRTR1 (0.37) | HCRTR1HCRTR2MEN1KMT2AKCNH2 | |
| SCHEMBL31479549 | 0.80 | HCRTR1 (0.35) | HCRTR1HCRTR2MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |