Styrene

Styrene

SCHEMBL3148003

C=Cc1ccccc1.CCCC(C=Cc1ccccc1)CC

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
CYP3A4 P08684 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
HTR2A P28223 3/20 0.34
RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL488956 0.92 MEN1 (0.46) MEN1KMT2AALDH1A1HDAC3HDAC4
Styrene SCHEMBL3151646 0.90 MEN1 (0.53) MEN1KMT2AALDH1A1TSHRCYP3A4
SCHEMBL9426848 0.80 MEN1 (0.51) MEN1KMT2AALDH1A1HTR2ARELA
SCHEMBL489091 0.80 MEN1 (0.43) MEN1KMT2ATSHRHDAC3HDAC4
SCHEMBL9620000 0.80 MEN1 (0.43) MEN1KMT2ATSHRHDAC3HDAC4
SCHEMBL489041 0.78 HDAC3 (0.41) MEN1KMT2ATSHRHDAC3HDAC4
SCHEMBL28332075 0.78 MEN1 (0.41) MEN1KMT2AALDH1A1HDAC3HDAC4
SCHEMBL4299524 0.77 EGFR (0.41) MEN1KMT2AHDAC3HDAC4HDAC1
SCHEMBL236417 0.75 EGFR (0.43) MEN1KMT2AALDH1A1HDAC3HDAC4
SCHEMBL10703015 0.75 EGFR (0.43) MEN1KMT2AALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675927-B1 COMPOSITION AND METHOD RELATING TO A HOT MELT ADHESIVE FULLER H B LICENSING FINANC (US) 2010-02-17 EP disclosed
US-20070082973-A1 Composition and method relating to a hot melt adhesive H.B. FULLER LICENSING & FINANCING, INC. 2007-04-12 US disclosed
US-7173076-B2 Composition and method relating to a hot melt adhesive H.B. FULLER LICENSING & FINANCING INC (US) 2007-02-06 US disclosed
EP-1675927-A1 COMPOSITION AND METHOD RELATING TO A HOT MELT ADHESIVE H.B. FULLER LICENSING & FINANCING, INC. (US) 2006-07-05 EP disclosed
WO-2005023951-A1 COMPOSITION AND METHOD RELATING TO A HOT MELT ADHESIVE H.B. FULLER LICENSING & FINANCING, INC. (US) 2005-03-17 WO disclosed
US-20050049342-A1 Composition and method relating to a hot melt adhesive ROYAL ADHESIVES AND SEALANTS, LLC 2005-03-03 US disclosed