Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26234226 | 0.85 | MAPT (0.52) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30587541 | 0.82 | MAPT (0.51) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1691036 | 0.82 | MAPT (0.51) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23751 | 0.81 | MAPT (0.43) | MAPTRAB9ANPC1MAPKAPK2SMN1; SMN2 | |
| SCHEMBL26131195 | 0.81 | MAPT (0.41) | MAPTRAB9ANPC1MAPKAPK2SMN1; SMN2 | |
| SCHEMBL22151008 | 0.80 | RAB9A (0.53) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11746859 | 0.79 | MAPT (0.44) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18952439 | 0.78 | MAPT (0.49) | MAPTRAB9ANPC1MAPKAPK2SMN1; SMN2 | |
| SCHEMBL15536991 | 0.78 | MAPT (0.51) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2634411 | 0.77 | RAB9A (0.63) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |