Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 9/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11355071 | 1.00 | TSHR (0.46) | TSHRALDH1A1TDP1THRBGGPS1 | |
| SCHEMBL95578 | 1.00 | TSHR (0.46) | TSHRALDH1A1TDP1THRBGGPS1 | |
| SCHEMBL3169691 | 0.97 | TSHR (0.48) | TSHRALDH1A1TDP1THRBGGPS1 | |
| SCHEMBL763414 | 0.89 | — | — | |
| SCHEMBL20299935 | 0.81 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL9576868 | 0.81 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL7208110 | 0.81 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL20299931 | 0.81 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL6658765 | 0.81 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL11699499 | 0.81 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256418-A | The benzamide that 1,3- thiazol-2-yl replaces | 拜耳公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-109111430-A | A kind of Dexlansoprazole crystal form A and preparation method thereof | 江苏豪森药业集团有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-107207507-A | 1, 3-thiazol-2-yl substituted benzamides | 拜耳公司 | 2017-09-26 | — | — | CN | disclosed |
| US-8212046-B2 | Process for producing crystal | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20100004458-A1 | PROCESS FOR PRODUCING CRYSTAL | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-07 | — | — | US | disclosed |
| CN-100562318-C | Crystalline preparation method | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2009-11-25 | — | — | CN | disclosed |
| US-7569696-B2 | Process for producing crystal | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20080306118-A1 | Process for the crystallization of (R) - or (S) - Lansoprazole | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-11 | — | — | US | disclosed |
| US-7285668-B2 | Process for the crystallization of (R)- or (S)-lansoprazole | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-10-23 | — | — | US | disclosed |
| US-7169799-B2 | Process for producing crystal | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-30 | — | — | US | disclosed |
| US-20070004779-A1 | Process for producing crystal | HASHIMOTO HIDEO | 2007-01-04 | — | — | US | disclosed |
| CN-1280287-C | Method for producing crystal | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-10-18 | — | — | CN | disclosed |
| CN-1803137-A | Process for producing crystal | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-07-19 | — | — | CN | disclosed |
| US-20040049045-A1 | Process for the crystallization of (r)-or (s)-lansoprazole | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-11 | — | — | US | disclosed |
| CN-1437592-A | Method for producing crystal | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-08-20 | — | — | CN | disclosed |
| US-20030153766-A1 | Process for producing crystal | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-08-14 | — | — | US | disclosed |
| CN-1081675-A | By the new pyrethroid of thiazolic alcohol derivative, its preparation method and as the purposes of agricultural chemicals | ROUSSEL UCLAF (FR) | 1994-02-09 | — | — | CN | disclosed |